Monthly Archives: March 2012

Welcome JIDC Brazil Regional Office!

JIDC opens Brazil Regional Office!

It is with great joy that we announce the opening of the JIDC Regional Office in Brazil!

When I was in Sardinia doing a part of my PhD project (My JIDC Post), I had the opportunity to participate in a JIDC meeting that took place in Stintino. It was fascinating, because I could see firsthand how a scientific journal operates and also how much work is behind these publications.
When I returned to Brazil, I thought several times about proposing to Professor Salvatore Rubino the establishment of a JIDC regional office in Porto Alegre. Publishing is very important for our country as well as other countries that are aiming to establish themselves. Also, when I looked through the JIDC archives, I noticed that there were few publications focusing on research conducted in Latin America by Latin American scientists.

In July 2011, I had the opportunity to return to Sardinia (this time for a wonderful vacation) and reconnected with old friends Marco Scano and Giustina Casu as well as meet new friends in Sassari. When I learned that they were going to Argentina for a holiday, I suggested they to come visit me in Porto Alegre to take advantage of a conference at the University where I am taking PhD (UFRGS) to speak a little of JIDC. We spent five wonderful days during which Marco talked to the students and teachers in my graduate program about the submission of papers and also the published JIDC items online. On this visit, we started talking a little more seriously about the creation of a JIDC regional office in Porto Alegre.

And here we are! Announcing the arrival of the Regional Office! Wonderful, is not it? The JIDC Brazil Regional office is strategically settled in the Food Microbiology and Food Control Laboratory, located in the Food Science and Technology Institute of the Federal University of Rio Grande do Sul (ICTA/UFRGS). This Institute was the first specialized food institute of Brazil, founded in 1958.

ICTA/UFRGS offers diverse undergraduate courses in areas such as food engineering, nutrition, pharmacy, chemical engineering, chemistry, and biomedicine in addition to several graduate courses related to food science and food technology working toward Masters and PhD degrees s in Food Science and Technology. The faculty has strongly collaborated with the post-graduation programme in agricultural and environmental microbiology.
The Food Microbiology and Food Control Laboratory of ICTA/UFRGS has several research projects, mostly linked to the investigation of food pathogens and food safety. The projects focus on solving food industry, food services and governmental problems related to food production. The head of this Laboratory is Professor Dr. Eduardo Cesar Tondo, who has been working with Food Microbiology and Food Quality for almost two decades, and is a research collaborator of Prof. Dr. Salvatore Rubino of Università Degli Studi di Sassari.
The main objective of the Brazil Regional office is to promote JIDC awarenessamong scientists, medical doctors, students and the general community of Brazil and neighboring countries, as well as to help all the colleagues of JIDC in scientific activities related to Brazil and Latin America.
We happily acknowledge the visit by Marco and Giustina, cultured and wonderful people, who showed great curiosity to know our country and customs. We are grateful to Marco Scano for his informative seminars which solidified the decision to implement the regional office in Porto Alegre. We especially thank Dr. Salvatore Rubino and the rest of the JIDC team for their confidence in our ability to join them in their endeavours.

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So much science and so little time! Suggestions from Salvatore Vol. I

So much science and so little time! Every month, JIDC Editor-in-Chief Salvatore Rubino sends me news events that interest him and that he thinks would make good blog content.   Unfortunately it’s impossible for me to write a column for each one.  So here we are with lots of interesting stuff that is not getting out.  This, I have decided, is not acceptable!

To remedy this, I am introducing a new section to the JIDC Blog call Suggestions from Salvatore.  Each month you can see all of Salvatore Rubino’s recommendations in one place.  Here are his recommendations for February 2012:

Bulletin of the World Health Organization — Volume 90, Number 3, March 2012, 157-244

The first recommendation from Salvatore in February is the paper “The global burden of cholera” from the March 2012 issue of the WHO Bulletin.  This paper was authored by Ali M and colleagues and describes the age-specific estimates of the cholera burden in endemic and non-endemic areas. From the authors’ calculations, approximately 1.4 billion people are at risk for cholera in endemic areas with ~91 000 cholera deaths each year with the majority of the infections being in children 4 years (as opposed to months or weeks?) and under. Furthermore an estimated 87 000 cholera cases and 2500 deaths are associated with cholera in non-endemic countries.  The authors conclude that these findings are important for the establishment of public health strategies.

http://www.who.int/bulletin/volumes/90/3/en/index.html

London Declaration on Neglected Tropical Diseases

Salvatore’s second suggestion was an article on the signing of the London Declaration on Neglected Tropical Diseases. Bill Gates and people from several large pharmaceutical companies and other global health agencies signed the declaration, which focuses on what can be done to eradicate NTDs. This story comes from Dr. Mark Booth’s article in the New Statesman, and it’s a great write-up of the current situation.

http://www.newstatesman.com/healthcare-and-pharmaceuticals/2012/02/research-ntds-health-infection

WHO-Global Foodborne Infections Network (GFN)

We next have the The WHO- Global Foodborne Infections Network (GFN).   This is a program established in 2001 that aims to combine laboratory based surveillance with the public human health, veterinary, and food-related outreaches. The Network’s five-year plan was discussed previously at a Strategic Planning Meeting in Lyngby, Denmark, in August 2010. You can read the published Strategic Plan 2011-2015 here

http://www.who.int/gfn/publications/strategic_plan_2011/en/index.html

 New Grant Program for Global Immunization and Strategy from the Bill & Melinda Gates Foundation

Lastly we have a call for applications from the Bill & Melinda Gates Foundation for a grant on the development of an easy-to-use-tool for the assessment of the childhood immune system.  The application should outline the tool’s development and commercial plans.  All applicants are welcome.  The deadline for applications is 10 a.m., March 27, 2012.  You can read more about this opportunity and the challenges here:  www.gatesfoundation.org/vaccines/Pages/rfp-immunity-assessment-tool.aspx.

 And a recommendation from me! Immune Response, Toll Like Receptors (TLR) Pathway – IMGENEX movie

I am going to sneak in a recommendation from me here.  I saw this video on the internet this week.  It is from IMGENEX was a fun take on the TLR pathway.  Enjoy!

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TB & HIV in South Africa — They Go To Die Film Documentary by Jonathan Smith

A couple of months ago, I received this incredible story in my email.  I was asked to help distribute information for the film documentary They Go To Die, and I immediately thought of posting it for the JIDC special TB Issue.

Jonathan Smith is an epidemiologist, who also has a special interest in each life that exists behind the statistics.   His work focuses on the problem of TB and HIV co-infection among gold miners in South Africa.  Importantly, not only does Jonathan strive to describe the scientific problem, he also wishes to tell the stories of the mine workers who have contracted these diseases.  This compelling project has culminated in the production of a film documentary, They Go To Die, of the miners and their families as Jonathan lives and works with them in South Africa.

What really drew me to Jonathan and his project was that I felt he shared the same vision and goal I had when I started the JIDC Blog.  This goal was to share the stories of the human lives behind the science.  Below is the Press Release that was sent to me.  Also, you can see an introductory video to his Film here:

Alyson

 

For Immediate Release

Unique approach to conveying research stirs public interest in HIV/TB epidemics

Media project catches the attention of TB/HIV experts

NEW HAVEN, CT – October 3, 2011 – Among researchers around the globe seeking to find a solution to the world’s growing TB/HIV epidemics, one researcher at Yale University is taking a slightly different angle.

Jonathan Smith, a lecturer in Epidemiology of Microbial Diseases and Global Health at the Yale School of Public Health who focuses on TB and HIV among South African gold miners, has turned to artistry and visual media to convey the urgency of these concomitant epidemics. Visually presenting his research experience in a documentary film titled, They Go to Die, he is uniquely seeking to surface complex health and legal issues associated with these devastating epidemics though the prism of life, family relationships, and community.

“Health research has become a statistical argument about a gain or loss of numbers. Statistics are undoubtedly important because they highlight the gravity of a situation. But ‘mortality’ doesn’t simply mean someone dies, it means an individual is removed from a greater, organic infrastructure of family and community. The effect of this removal is something that you can’t relegate to the confines of an academic journal, much less verify with p-values,” Smith states, describing his approach.

Smith, who began the project as a graduate student at Yale, self-funded and self-organized two separate trips to southern Africa for the film’s production. After a year and a half of organizing, working several part time jobs, and a crash course in filmmaking, he left for Africa to live with the families of four former mine workers coinfected with TB and HIV. There he became immersed in their lives – even sleeping in the same communal bed with the families and garnering a traditional name, ‘Masheshay’nike.’ During this time, he documented their daily lives in order to understand how former mine workers and their families cope with life at home with TB/HIV.

Jonathan Smith during the production of his project

 

South African mines have long been synonymous with disease. Informal and substandard living and working conditions underground lead to high rates of silicosis, a disease cause by silica dust produced in the mines, as well as TB. Living in hostel-style living conditions means intimacy is often only in the form of sex workers, which also puts miners at high risk for HIV infection. HIV and silicosis both act to increase TB susceptibility, but when combined, they multiplicatively increase the risk of TB infection.This ‘perfect storm of disease’ results in the highest rate of TB in the world: up to twenty-eight times a declared emergency set by the World Health Organization and three times higher than the highest burdened countries. Unfortunately, over ninety percent of the men are migrant workers and frequently oscillate between the mines and rural areas of southern Africa. This spreads the disease around the sub-continent with frightening efficiency: a recent study indicates that aside from HIV, South African mining is the largest driver of the TB epidemic in southern Africa and directly responsible for 760,000 incident cases of TB each year.

TB is perfectly curable and HIV is manageable with proper medication. However, when a worker becomes sick at the mine, their illness deems them ‘unfit for work,’ and legal complexities absolve corporate, governmental, and union-based accountability for the worker’s health and well-being. Subsequently, they are sent home to rural areas of southern Africa with no medication or means for continuation of care. Since these areas often have little or no access to medication, this process is colloquially termed, “sending them home to die.” It is this colloquial terminology where Smith derived the name of his film; a term that he feels highlights the complacency of the situation.

Without proper treatment, TB complicated by HIV kills with ease: eighty three percent of untreated, coinfected individuals will die, having an average life expectancy of only 6 months from onset of disease.

But don’t remind Smith of this. To him, it is all too real.

“These men were my friends. They invited me into their home and accepted me as family. Then they died a completely preventable death – so this is obviously personal to me. Needless.” he states, clearly affected.

Miner Friends of Jonathan

“Its frustrating. You hear it at every conference; every health official with a voice has deemed TB in the mines an ‘emergency’, ‘threat,’ or a “catastrophe.’ But lethargy and inaction deflect this hopeful rhetoric and reality shows the epidemics have only gotten worse. The unfortunate paradox is that this is a preventable and curable disease in a well-regulated industry with a competent government that can easily rectify the situation if there was enough political momentum,” he continues.

Smith’s approach, however, hopes to cut past the statistics and politics by uniquely focusing not solely on death, politics, or numbers, but on the importance of the individual’s life. “No one wants to watch a film about death and become depressed. We want to know there is hope, that there is a reason we should stop this, and that this can be surmounted,” he states. The film’s website goes on to explain, “They Go to Die surfaces issues of health, human rights, and legal complexities… nonlinearly though the context of life, love, and family. It is ultimately a story of humanity – a celebration of family and the power of relationships.”

The distribution plan for the film is also what makes the concept particularly lucrative. With eye-catching aesthetics and high production value combined with valid academic rigor, Smith hopes to make the film appealing to both a general audience as well as decision makers in the academic and governmental realm. This combination, for instance, would make it dually relevant at venues such as academic conferences and university lecture halls, as well as international film festivals, television, and other mainstream outlets.

“Most individuals are not decision makers, so motivating civil society is pointless without a means to release that energy; conversely, educating decision makers is pointless without accountability. This film will hopefully bridge both academia and civil society, and act to accurately inform decision makers while empowering civil society to remain as a watchdog,” Smith states in describing this unique model.

His approach seems to be working and is attracting attention from many leading public health officials.

“Jonathan has done something that most of us in academics rarely achieve,” says Dr. Kaveh Khoshnood, global health professor and HIV/AIDS researcher at Yale University. “[He tells] a compelling story that provokes action.”

Dr. Elizabeth Bradley, Director of Yale’s Global Health Initiative says of his project, “The key about Jonathan’s work is it is authentic. He really knows his stuff and captures reality in a way others have not. You are not the same after you see his film – a great piece of public health.” Dr. Bradley is world renowned for her work in health delivery and quality improvement.

Last May, Dr. Paul Cleary, Dean of the Yale School of Public Health, awarded Smith the distinguished Lowell S. Levin Award for Excellence in Global Health. Smith was also awarded the Yale Global Health Initiative Field Experience Award in 2010 for the project’s innovative approach to global health.

The project is currently in post-production, where Smith is using the website Kickstarter.com to crowd-source the $13,000 in funds needed to advance the project. Over 10,000 projects have been financed through Kickstarter since its founding in 2009, which allows individuals donations towards a variety of creative projects. To date, the project has raised $6,520 from 81 supporters, some of whom are those mentioned above, but per Kickstarter’s all-or-nothing policy he has only 21 days left to reach the goal or he will receive no funds at all.

But again, don’t tell Smith this.

“[Fundraising] is a necessary evil, and I’m trying to figure it out at the moment. It is not a question of ‘if,’ but of ‘how’ and ‘when.’ But I am acutely aware that money alone will not make this approach successful. Like any effort in public health, money is necessary, but it doesn’t equal change. We want the film to serve as a thread that weaves together interested organizations and individuals and mobilizes them to enact change. That will take commitment, teamwork, and dedication, not simply money,” he states.

“We could raise all the money in the world but if we don’t create action, quite frankly, the project is rendered pointless,” he continues.

Jonathan will be travelling through Canada and the United States in late October through December.  He is planning multimedia presentations and Q&A sessions at local campuses and other forums, and is looking for individuals and groups who would be interesting in attending these talks.

Now a lecturer at Yale, he hopes to teach and reproduce this model in other areas of global health. Smith states, “There are a number of global health issues that where data clearly delineates a need for change, but action seems to be absent. If we connect that statistical evidence with the power of humanity, then we can motivate the change needed to help those who need it most.”

Contact Information:

For more information about They Go to Die, visit: http://www.theygotodie.com

Jonathan can be reached at: jonathan.smith@theygotodie-movie.com

The They Go to Die kickstarter page can be found at: http://kck.st/ocZ5rn

If you (or your organization) is interested partnering with the film, please contact Jonathan Smith directly.

Press Release and Photos provided by BGS Horsman

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Filed under HIV/AIDS, Postcards, South Africa, Tuberculosis